natural DHT blockers

24 Natural DHT Blockers to Stay Away From

In Dihydrotestosterone by Marcel18 Comments

I don’t advocate natural DHT blockers and especially not natural DHT blockers. I advocate increasing DHT to the maximal. DHT is the greatest male hormone to have roamed the body. This post is to show you what to stay away from in terms of DHT.

DHT gets a lot of shit for prostate issues and hair loss. I haven’t seen a single conclusive study though. Some studies say its the DHT/testosterone ratio that causes hair loss, some say its low testosterone, and others say its high DHT. Bottom line is there is no conclusion.

Even if DHT cause hair loss, I don’t give a damn. Its just hair and nothing else. I’m going to stay far away from these 24 natural DHT blockers.

24 Natural DHT Blockers to Stay Away From

  1. Avocados, coconut oil, and olive oil
  2. Tomatoes, watermelon, carrots, and mangoes
  3. L-lysine
  4. Docosahexaenoic acid (DHA), gamma linolenic acid (GLA), and polyunsaturated fat
  5. Bran
  6. DIM in high doses
  7. Zinc in high doses
  8. Most teas
  9. Some spices
  10. Almost all nuts
  11. Green tea
  12. Azelaic acid
  13. Pumpkin seeds
  14. Saw palmetto
  15. Cacumen platycladi
  16. Giant dodder
  17. Rosemary
  18. Mint and peppermint
  19. Fenugreek
  20. Safflower
  21. Reishi
  22. Soy
  23. Black pepper leaf extract
  24. Alcohol

Avocados, Coconut Oil, and Olive Oil

Avocados are great for testosterone but not DHT. Avocados are one of the biggest natural DHT blockers out there.

Limit them because of a component found in them called beta sitosterol competes for cholesterol, leaving less cholesterol in your system that can be made into testosterone.

This study concludes that beta-sitosterol, found in avocados, coconut oil, and olive oil, is effective at inhibiting 5-alpha reductase.

This study concludes that beta sitosterol is effective at inhibiting the 5-alpha reductase enzymes as well.

Tomatoes, Watermelon, Carrots, and Mangoes

Tomatoes, watermelon, carrots, and mangos all have a component called lycopene.

This study found out that lycopene inhibits DHT naturally by down regulating or inhibiting 5 alpha reductase.

This study says – lycopene consumption inhibits IGF-I and androgen signaling in rat prostate cancer. In this study, lycopene, in dietary concentrations, reversed DHT effects of 6S cells on NPE cell death, decreased 6S cell IGF-I production by reducing AR and beta-catenin nuclear localization and inhibited IGF-I-stimulated NPE and PREC growth.

This study says – lycopene interfered with local androgen activation by down-regulating 5-alpha-reductase, the key enzyme for the transformation of testosterone to its most active form dihydrotestosterone (DHT). As a consequence, the expression of androgen-regulated target genes was also reduced.

This study found the same thing – lycopene inhibits IGF-1 and androgens.

In this study sham-operated rats provided with either phytofluene, lycopene, or tomato powder had ∼40–50% lower serum testosterone concentrations than the sham-operated, control-fed group. Modest changes in mRNA expression of steroidogenic enzymes with short-term carotenoid intake may alter the flux of androgen synthesis to less potent compounds.

There’s 2 more studies that conclude pretty much the same thing (study 1) (study 2).

L-Lysine

This study says – since propecia is a DHT inhibitor, the addition of a L-Lysine supplement can make these products also more effective. Studies has shown that L-Lysine combined with a DHT inhibitor can promote hair growth in people suffering from androgenetic alopecia.

This study notes an improvement of specificity of anti-testosterone (T) and anti-5 alpha-dihydrotestosterone (DHT) rabbit antibodies by immunotolerance techniques.

So foods to avoid packed with L-lysine are almonds, walnuts, peanuts, and pecans.

Docosahexaenoic Acid (DHA), Gamma Linolenic Acid (GLA), and Polyunsaturated Fat

You pretty much want to avoid ALL polyunsaturated fats and fatty acids for maximal dihydrotestosterone. Nothing good comes from polyunsaturated fats. Most nuts and a good amount of fish are the richest sources of polyunsaturated that you want to avoid or limit greatly.

This study found that dihydrotestosterone is suppressed by 15-lipoxygenase metabolites of gamma-linolenic and eicosapentaenoic acids.

This study‘s results are – gamma-linolenic acid, but not the corresponding saturated fatty acid (stearic acid), inhibited the 5 alpha-reductase activity, but not the 17 beta-dehydrogenase activity, of human prostate cancer cells in culture.

This study talks about all the specific fatty acids that inhibit 5ar. GLA is the most potent one.

Stay away from plant seed oils, blackcurrant, hemp oil, spirulina, and borage oil as those are all loaded with quantities of GLA (study).

This study confirms – GLA beats EPA in 5 alpha-reductase inhibition.

Bran

The most common bran source is brown rice. White rice is good, brown rice ain’t good.

This study says – O. sativa bran crude extract gave the highest content of unsaturated fatty acids and 5α-reductase (type 1) inhibition activity (5AR). Its linoleic acid (LN) and total unsaturated fatty acid (TUC) contents were significantly positive and linear correlated to 5AR. Its total phenolic contents and all biological activities also showed positive correlations to 5AR. The study concluded – O. sativa bran crude extract prepared by scCO2 to be developed as anti-androgenic alopecia products.

DIM in High Doses

DIM is great for lowering estrogen in men. There’s a downside to DIM though. It is anti-androgenic in higher quantities. DIM is found in cruciferous vegetables – cabbage, broccoli, cauliflower…

At high doses it becomes one of the 24 natural DHT blockers.

This study found some interesting things. DIM exhibits potent antiproliferative and antiandrogenic properties in androgen-dependent human prostate cancer cells. DIM suppresses cell proliferation of LNCaP cells and inhibits dihydrotestosterone (DHT) stimulation of DNA synthesis.

Moreover, DIM inhibited endogenous PSA transcription and reduced intracellular and secreted PSA protein levels induced by DHT in LNCaP cells. Also, DIM inhibited, in a concentration-dependent manner, the DHT-induced expression of a prostate-specific antigen promoter-regulated reporter gene construct in transiently transfected LNCaP cells.

Then there’s this study that confirms that – DIM has been found to inhibit 5 alpha reductase activity to varying degrees.

Don’t avoid DIM completely though. This study and many more found that DIM increased the 2-hydroxylation of estrogen urinary metabolites. Meaning it makes estrogen leave the body faster, leaving less bioavailability of the estrogen.

Zinc in High Doses

Zinc is slick. In high doses it inhibits 5ar but in low-moderate doses it increases 5ar enzymes. And being deficient in zinc messes up your 5ar. So zinc is one of the natural DHT blockers, but only in high doses.

This study says – when added at concentrations of 3 or 9 mmol/l (3 mnol/l = 54mg), zinc was a potent inhibitor of 5 alpha-reductase activity. At high concentrations, zinc could completely inhibit the enzyme activity.

This study shows that when zinc is added at low concentrations the 5 alpha-reduction of testosterone is increased but at higher cation concentrations the metabolism is significantly inhibited.

So to reap the increased 5ar benefits of zinc, take it in 10-30mg a day. Don’t go over 50mg because that’s when the 5ar inhibiting effects start.

Most Teas

Tea is way over-hyped and other than some herbal teas, tea is shit. Especially for dihydrotestosterone.

This study on animals found that green tea catechins have 5ar inhibiting effects. The study says exactly this – green tea catechins are 5alpha-reductase inhibitors and inhibited flank organ growth. However, (-)-epicatechin and (-)-epigallocatechin, which are not 5alpha-reductase inhibitors, also inhibited flank organ growth.(-)-epigallo-catechin-3-gallate also inhibited DHT-dependent growth of flank organs.

In another animal study, theaflavins found in black tea lowered DHT levels by 72% and 5ar levels by 89%. Theaflavin-3,3′-digallate and penta-O-galloyl-beta-D-glucose inhibit rat liver microsomal 5alpha-reductase activity. They significantly reduced androgen-responsive LNCaP prostate cancer cell growth, suppressed expression of the AR and lowered androgen-induced prostate-specific antigen secretion and fatty acid synthase protein level.

This study confirms – green tea contains potential DHT-blocking nutrients. Within tea leaves are two compounds, epicatechin-3-gallate, and epigallo-catechin-3-gallate (EGCG), which have been shown to inhibit 5 alpha-reductase activity.

Some Spices

A lot of spices have shown 5ar and dihydrotestosterone inhibiting effects. Not a big deal since spices aren’t used in huge quantities, but if you want maximal dihydrotestosterone you’re going to want to drop the spices or limit them.

This study says curcumin has been shown to specifically inhibit 5 alpha reductase type 2.

This study says – natural compounds, including alizarin and curcumin, are 5alpha-reductase inhibitors and inhibited flank organ growth.

Then these 2 studies say the same thing (study 1) (study 2).

Almost All Nuts

Most nuts have a good amount of phytosterols (basically the plant version of cholesterol). We’re going to be focusing on phytosterols’ effect on DHT.

This study concluded fatty acids and phytosterols in saw palmetto extract has an anti-androgenic effect.

This study says – limited evidence from animal studies suggests that very high phytosterol intakes can alter testosterone metabolism by inhibiting 5α-reductase.

This study‘s results – feeding 2% phytosterols with 0.2% cholic acid to rats for 22 days resulted in a 33% reduction in serum testosterone compared with controls, which received only 0.2% cholic acid in the diet. 5-α-Reductase was reduced by 41 to 44% and 33% in the liver and prostate, respectively.

This study concluded – the consumption of phytosterols is linked to low concentrations of androstenedione.

Remember, androstenedione converts to 5a-androstanedione, which then into the mighty DHT. So we want androstenedione. After seeing these studies, you can see that nuts have no place in increasing DHT.

Green Tea

Green tea is a big time natural DHT blocker.

Most teas are shit. Green tea is the shit – #1 shittiest tea.

This study on animals found that green tea catechins have 5ar inhibiting effects. The study says exactly this – green tea catechins are 5alpha-reductase inhibitors and inhibited flank organ growth. However, (-)-epicatechin and (-)-epigallocatechin, which are not 5alpha-reductase inhibitors, also inhibited flank organ growth.(-)-epigallo-catechin-3-gallate also inhibited DHT-dependent growth of flank organs.

This study confirms – green tea contains potential DHT-blocking nutrients. Within tea leaves are two compounds, epicatechin-3-gallate, and epigallo-catechin-3-gallate (EGCG), which have been shown to inhibit 5 alpha-reductase activity.

Azelaic Acid

Azalaic acid is an acid that is naturally found in wheat, barley, and rye. Just any kind of bread has this acid.

This study says – azelaic acid was also a potent inhibitor of 5 alpha-reductase; inhibition was detectable at concentrations as low as 0.2 mmol/l and was complete at 3 mmol/l. Azalaic acid, a high dose of zinc, and vitamin B6 when added together at very low concentrations, 90% inhibition of 5 alpha-reductase activity was obtained.

Pumpkin Seeds

This study says – although the action mechanism is still unclear, previous animal studies have suggested that PSO may inhibit 5α-reductase.

This study confirms – pumpkin seed oil (PSO) has been shown to block the action of 5-alpha reductase and to have antiandrogenic effects on rats. Mean hair count increases of 40% were observed in PSO-treated men at 24 weeks.

Saw Palmetto

Saw Palmetto is one of the most effective natural DHT blockers, probably THE most effective from all the natural DHT blockers.

Everyone that has even a slight interest in increasing DHT knows that saw palmetto is something to stay far away from, real far away.

This study demonstrated that by blocking the conversion of T to DHT, with either pharmaceuticals or natural compounds, the circulating level of DHT is reduced by 80%, the size of the prostate gland is reduced by about 20% and the level of prostate-specific antigen (PSA) drops by about 50%.

This study‘s results show astaxanthin, a component in saw palmetto, demonstrated 98% inhibition of 5alpha-reductase at 300 microg/mL in vitro.

This study confirms – the lipophilic extract from saw palmetto berries inhibits the binding of DHT.

This study says – saw palmetto’s primary therapeutic action is to inhibit 5-alpha reductase in forming DHT and to a lesser extent, 3-alpha reductase, and to block the action of DHT to receptors on prostate cells via 3-ketosteroid reductase.

Saw palmetto is a piece of shit herb. Nothing else to say about it.

Cacumen Platycladi

Cacumen platycladi is the Chinese saw palmetto. Not too many studies on it since its new, but this herb will hit headlines as a hair restoration product soon.

This study found that cacumen platycladi showed strong 5αR inhibitory activity. cacumen platyclai possesses high hair growth promoting activity in the in vivo androgen-sensitive mouse model via inhibiting the 5αR activity, decreasing the DHT levels and in turn suppressing the expression of 5αR.

Giant Dodder

Giant Dodder is one of the most effective natural DHT blockers.

The name “giant dodder” makes me picture a huge baby. A huge baby with low DHT.

This study says – the most common herbs used to inhibit DHT production are green tea, saw palmetto, pumpkin seed, and giant dodder. Giant Dodder is an herb that had been used in the ancient Indian system Ayurveda to fight hair loss. Giant Dodder contains anti-androgen properties. It was found Giant Dodder contains compounds that are able to inhibit 5-alpha-reductase type II.

Rosemary

Roses are red, violets are blue, rosemary lowers DHT, so stay far away from that too.

This study says – in test tube studies, the rosemary extract inhibited the activity of 5-alpha reductase up to 94.6%.

This study found out that some compounds found in rosemary showed potent inhibitory activity towards 5α-dihydrotestosterone.

Then this study concludes all that. In this study rosemary showed inhibitory activity of 82.4% and 94.6% at 200 and 500 µg/mL, respectively. As an active constituent of 5α-reductase inhibition, 12-methoxycarnosic acid was identified with activity-guided fractionation. In addition, the extract of R. officinalis and 12-methoxycarnosic acid inhibited androgen-dependent proliferation of LNCaP cells as 64.5% and 66.7% at 5 µg/mL and 5 μM, respectively.

Mint and Peppermint

This study concludes that spearmint tea is anti-androgenic.

This study done on women who drank spearmint tea found that after 30 days of drinking spearmint tea, total testosterone and free testosterone reduced significantly.

Fenugreek

This study found out that fenugreek increased testosterone and bioavailable testosterone, but not DHT.

Then this study shows – 45 resistance trained males consuming 500mg fenugreek extract experienced a decrease in DHT with no significant affect on bioavailable testosterone or other measured hormones.

This next study found something similar. Supplementation of fenugreek extract resulted in a 9.42% decrease in serum dihydrotestosterone (DHT) levels in comparison to placebo. Other anabolic and metabolic hormone analyses were not affected by supplementation.

So fenugreek might increase testosterone, but that increase comes from inhibiting the testosterone to dihydrotestosterone conversion.

Safflower

Safflower is one of the most effective natural DHT blockers as well.

This study says safflower could be used as new potential therapeutic candidate for the treatment of androgen-related diseases.

This study says – safflower is the most potent 5α-reductase inhibitor and hair growth promoter followed by Phyllanthus emblica.

Safflower has a good amount of linoleic acid as well. And as you know, linoleic acid is a 5ar inhibitor.

Reishi

Reishi is a mushroom thought to have many health benefits. There’s a big downside though.

This study says – in a research study exploring the anti-androgenic effects of 20 species of mushrooms, reishi mushrooms had the strongest action in inhibiting testosterone. Reishi mushrooms significantly reduced levels of 5-alpha reductase, preventing conversion of testosterone into the more potent DHT.

This next study confirms that – reishi showed the strongest 5-reductase inhibitory activity. The treatment of the fruit body of reishi or the extract prepared from it significantly inhibited the testosterone-induced growth of the ventral prostate in castrated rats.

Soy

This is nothing new and I’m sure everyone knows soy is a pile of shit, but I’ll list it anyway because a lot of people consume soy without even knowing it. Read the ingredients label on every product in your house and you’ll see what I’m talking about.

This study found out that soy and other phytoestrogens act as 5-a inhibitors.

This study found out that isoflavones (genistein, daidzein and glyciteinin) in soy are the worst offenders of DHT.

Then this study concluded – soy protein, regardless of isoflavone content, decreased DHT and DHT/testosterone with minor effects on other hormones.

Black Pepper Leaf Extract

This study found – P. nigrum leaf extract showed in vivo anti-androgenic activity using the hair regrowth assay in testosterone sensitive male.

Alcohol

Ethanol is the principal type of alcohol found in alcoholic beverages, produced by the fermentation of sugars by yeasts.

This study found – ethanol increased DHT conversion to 3 beta – and 3 alpha-diol, in direct relation to the dose of ethanol added. The study concluded that ethanol may decrease the availability of the proposed active androgen.

This study says that ethanol reduced androgen receptors, serum LH and testosterone, resulting in impairment of the androgen-induced sexual events and a suppression of the pituitary gonadotropin secretion.

This study says – ethanol treatment significantly reduced the epididymal tissue/sperm carnitine, acetyl carnitine, GPC, and sialic acid.

All these changes were reverted back to normalcy after withdrawal of ethanol treatment, indicating the transient effects of ethanol. In conclusion, it is evident that ethanol has an adverse effect on sperm maturation, which may be affected due to the decrease in serum/epididymal testosterone and DHT levels.

There you have it – 24 natural DHT blockers. Stay far, far away from these 24 natural DHT blockers.

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Comments

  1. Marc

    You recommend avoiding DHA but at the same time in the article “Natural Herbs and Supplements That Actually Work Part 2” you recommend the use of cod liver oil … which contains DHA. How do you reconcile this contradiction?

    1. Author
      Marcel

      Depends on your goals – you want maximum DHT, don’t take it. You’re more focused on health, take it.

      Cod liver oil is something you use for a short period of time to balance out the omega 3 to 6 ratio. It will inhibit 5 alpha during usage but then a better balanced omega ratio will lower inflammation and increase testosterone.

      A lot of good stuff inhibit 5 alpha and you can’t drop all of them since some have essential compounds.

      1. javidbencosme

        You should mention that in this article, you list dha but dont talk about it in detail like you did for poly fats, my question is i see foods with dha is fish which you say to avoid because of the poly fats, but then there is meat organ meat and eggs that have it to, these foods are supposed to be good for t but they have dha? Please clear this up thank you, i hope you go into detail in your book

      2. JB

        It’s absurd to recommend avoiding DHA. It’s an essential fatty acid of immense importance and you’re sure to find in lists about increasing T and lowering SHBG to recommendation to take fish oil. When seeing long lists like this it’s best to avoid the most violent offenders before you begin shunning all food for barely a noticeable change in endocrine function. Many of these I agree with, but fish oil–fish being probably the oldest consumed animal food–is essential for health. Avoid the primary offenders here people, and to say that you either maximize DHT or maximize health: no… without maximal health your free test will dip, as reproductive function is first to go when health goes.

  2. BombDaDoge

    Lol, not sure how I got here…just randomly searching for a natural DHT blocker. You mention why DHT blockers are bad and what supposedly blocks them, which half of these don’t do anything to DHT…but, you never explain why DHT is good for the body. I have male pattern baldness and most medical scientists agree that high levels of DHT is causing hair follicles to become sensitive to it and essentially miniaturize and fall out then potentially never grow back again unless some stimulating chemical is add on the follicle.

    Where exactly did you get your information from? If you’ll ever read this, I suggest doing more research next time.

    1-Saw Palmetto has been shown to be as effective as a placebo.

    2-Most tree nuts will not harm DHT in anyway whatsoever. If that were the case doctors would promote it for hair-loss.

    3-“Some spices” which ones? I mean I don’t know if you’re referring to turmeric or what.

    4-Again, green tea is one of those controversial things that people claim it works. Very weak science exists to support its DHT blocking roll in men.

    5- Food in general barely does anything for DHT. Studies conducted on the effect of DHT using a combination of healthy fruits and veggies found that it only touched DHT ever so slightly but in the over all run, it didn’t do Jack sh*t. Most doctors also dismiss this wild notion that any single food could even block DHT.

  3. Commenter

    Are you aware that Green Tea *raises* DHT? (in contrast to Black Tea)

    Here, this study is well-known on Hair Loss forums:
    http://jn.nutrition.org/content/133/2/516.full.pdf

    “Green tea did not reduce the serum level of DHT but tended to increase it” — by like 190%. So green tea is actually quite pro-androgenic, not anti-androgenic. On the other hand Black Tea is anti-androgenic.

        1. Author
          Marcel

          Well you want both DHT in serum and tissue so messing up this balance (as green tea might) wouldn’t be “androgenic”.

  4. vks

    what about Caster oil. Is it safe to apply topically to hair without jeopardizing DHT production.

  5. Carlos prowse

    Man your mad.Why wouldn’t you want hair on your head,or is it more important to walk around looking like a bald headed,muscle bound Neanderthal.At the end of the day when your older all that muscle will turn to flab and guess what you also won’t have any hair.I’d rather walk around looking lean and fit with plenty of hair on my head Thankyou very much.Also it sounds like you don’t want anything competing with your cholesterol,so I guess you want high cholesterol then.Your full of contradictions and nothing you say makes any sense to me.

    1. Author
      Marcel

      I have a full head of hair and good amount of muscle, though I don’t care for either much.

      Your cholesterol won’t be high if it’s metabolizing into steroids effectively.

      Maybe you lack proper cognitive function for it to make sense or you don’t want it to make sense.

  6. Sean

    Everything is pretty accurate, except the coconut oil/extra virgin olive oil. I would be surprised if those were true, but your citations as evidence are rather weak.

  7. your name

    Youre falling into the typical alt medicine trap of believing that singilar, unreplicated studies are DEFINITIVE proof of anything. You’re also making the wild assumption that just because a single ingredient in a food has been shown to inhibit dht 5ar, that consuming the whole food, with its 100s of other components, will result in the same effect. I mean really, avoiding coconut oil and fish? How could anyone seriously come to that conclusion.

  8. Someone

    Who the hell wrote this? Propecia’s CEO?

    I’ve been doing topical olive oil and topical Onion juice daily on my crown, each one on a separate day , it’s been two weeks and my hair is growing back already, the little hairs that are already there but weak and invisible, along side healthy eating in general and healthy sleep and no bad habits, no sides so far and probably well not get any since it’s all topical

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